Mental Health
It is known that more intensive management of hypertension can improve blood pressure control and thus improve cardiovascular outcomes. However, there are several different systems of measuring the intensity of management of hypertension, and they have not been previously compared. If one system performs best, it would be important to use it to measure intensity of management for research and quality improvement purposes. Researchers from Boston University have compared different measures of treatment intensity in hypertension care and have found that one of the measures should be preferred to the others. This study, which appears in the July issue of Circulation: Cardiovascular Quality and Outcomes, shows that the measure originally described by Okonofua, et al. (Hypertension, 2006) predicts blood pressure control more effectively than the other two measures studied.
Human tissues normally discarded after surgical procedures could be a rich additional of stem cells for regenerative medicine. New research from BioMed Central"s open access Journal of Translational Medicine shows for the first time that human fallopian tubes are abundant in mesenchymal stem cells which have the potential of becoming a variety of cell types.
A polyomavirus known as MCPyV is associated with clinical outcomes, including fewer metastases and better survival, in patients with a rare form of skin cancer called Merkel cell carcinoma, according to a new study published online June 17 in the JNCI.
The saying "Knowing is half the battle" is never more true than when discussing early treatment of disease. Muscular dystrophy is one such disease where patients can benefit from early treatment. Now, new research is moving doctors and scientists closer to disease diagnosis in advance of patient symptoms.
Brian Andrew Tully, Esq., an attorney specializing in elder law, argues against POLST (Physicians" Orders for Life-Sustaining Treatment). In his article "A Counterview: Objections to the POLST Paradigm," which was published in the February 2009 issue ofThe Elder Law Report, Mr. Tully states that POLST gives physicians autonomy in the decision-making process, without having to consult with the patient or the health care proxy.
Researchers have identified a new candidate tumor suppressor gene in colorectal cancer and examined its use as a potential biomarker in stool samples, according to a new study published online June 17 in the Journal of the National Cancer Institute.
Gastroenteritis means irritation and inflammation of the gastrointestinal tract, which includes the stomach and small and large intestines. The condition is usually due to bacteria, food poisoning, parasites, or viruses, and it often results in diarrhea, abdominal pain, nausea, and vomiting. Gastroenteritis is commonly called gastric flu or stomach flu although it has no relation to the influenza virus.
Forty-six percent of patients over age 60 currently on the waiting list for a kidney transplant will die before they receive an organ from a deceased donor, reports an upcoming study in the Clinical Journal of the American Society of Nephrology (CJASN). "Our results emphasize the particular need to consider living donation as an alternative for some older patients or alternatively, the critical importance of navigating the steps to receive a deceased donor transplant as rapidly as possible," comments Jesse D. Schold, PhD (University of Florida, Gainesville).
Osmetech (LSE:OMH) announced that it has submitted a request to the US FDA for Emergency Use Authorization (EUA) for its Respiratory Pathogen Test Panel test to be used to screen for the swine flu virus.
The new application syngo iFlow from Siemens Healthcare makes it possible for the first time to
Thousands of unregistered Rohingya refugees living in the Kutupalong makeshift camp, Bangladesh, are being forcibly displaced from their homes, in an act of intimidation and abuse by the local authorities. The international medical organization Doctors Without Border/Mç©decins Sans Frontiç¨res (MSF) has treated numerous people for injuries, of which the majority were women and children. Furthermore, MSF has witnessed countless destroyed homes and heard many reports of people being warned to remove their own shelters or face the consequences.
Senators delayed work Wednesday on one health care reform bill and hit partisan roadblocks on another as key lawmakers insisted they are still on track to have a bill on the floor by the middle of summer, The Washington Post reports.
Mathematica Policy Research: The National Health Plan Collaborative: Overview Of Its Origins, Accomplishments And Lessons Learned
There may be thousands of things large and small that can be done to better control pollution on even the smallest waterways, and a new tool developed at Purdue University may help sort out how to choose the best ones.
The National Infertility Awareness Campaign (NIAC) welcomed the document "Standardising Access Criteria to NHS Fertility Treatment"1 produced by Infertility Network UK (I N UK) and funded by the Department of Health.
Most healthy 25 year olds don"t stay up at night worrying whether they are going to develop diabetes in middle age. The disease is not on their radar, and middle age is a lifetime away.
Natural Standard Research Collaboration invites researchers to submit articles to Journal of Dietary Supplements (JDS) - an international peer-reviewed forum for original research and review articles that focus on vitamins, minerals, herbs and other substances that make up the multi-billion dollar dietary supplement industry. The journal addresses important issues that meet a broad range of interests - not only in integrative healthcare, but also in academic, regulatory and industrial sectors.
Some parents may be unnecessarily switching infant milk formulas for their healthy infants. A study published in BioMed Central"s open access Nutrition Journal, found that many parents misinterpret common baby behaviors as milk intolerance and needlessly switch formulas without consulting a health professional.
Light touch - the sense that lets musicians find the right notes on a keyboard, a seamstress revel in the feel of cool silk, the artisan feel a curve in material and the blind read Braille - truly depends on the activity of Merkel cells usually found in crescent-shaped clusters in the skin, said researchers from Baylor College of Medicine and colleagues in a report that appears in the current issue of the journal Science.
The Juvenile Diabetes Research Foundation said recently that for the fourth time in 18 months, one of its biotech partners has signed a collaboration agreement with a large pharmaceutical company to move research on type 1 diabetes into the final phases of trials.
Human Genome Sciences, Inc. (Nasdaq: HGSI) announced that Novartis has completed enrollment and initial dosing in a Phase 2b clinical trial to evaluate the safety and efficacy of Albuferon(R) (albinterferon alfa-2b) administered monthly in combination with ribavirin in treatment-naive patients with genotypes 2 and 3 chronic hepatitis C. Albuferon is being developed by HGS and Novartis under an exclusive worldwide co-development and commercialization agreement entered into in June 2006.
Families of Spinal Muscular Atrophy has just released details of the latest developments for the Families of SMA funded therapeutic pipeline.
Accuray Incorporated (Nasdaq: ARAY), a global leader in the field of radiosurgery, announced that the Turkish Ministry of Health has purchased two CyberKnife(R) Robotic Radiosurgery Systems for installation in Ankara and Istanbul, Turkey.
The American Lung Association released its State of the Air: 2009 Report this month. The 10th annual report states that air pollution has significantly improved in some areas of the country, but major cities still have significant problems with pollutants.
Studies performed in three animal models confirmed the safety and intensive immunogenicity of a new type of intranasal H5N1 influenza vaccine, according to the latest preclinical study data announced today by the Vienna based firm, Avir Green Hills Biotechnology. The study data was just published in PloS One, the Public Library of Science.
Seattle Genetics, Inc. (NASDAQ:SGEN), announced that it has initiated a phase II clinical trial of SGN-35 for patients with relapsed or refractory systemic anaplastic large cell lymphoma (ALCL). SGN-35 is an antibody-drug conjugate (ADC) that utilizes Seattle Genetics" proprietary technology to empower antibodies by linking them to potent cell-killing drugs.
The European Medicines Agency is inviting comments on its draft
World hunger is projected to reach a historic high in 2009 with 1 020 million people going hungry every day, according to new estimates published by FAO today.
Women are under too much pressure to lose weight quickly after giving birth, according to German Institute
Food supplementation programs for women, infants and children are among the strategies that should be trialled to improve nutrition in Indigenous communities, according to an editorial published in the May 18 Indigenous Health issue of the Medical Journal of Australia.
HHS Secretary Proclaims: "Single-Payer is Not Part of the Discussion" Allows Health Insurance Corporations to Continue Patient Abuses
CNN examines race disparities in health care during a 4-minute segment that is part of the station"s week-long focus on health care issues.
The Houston Chronicle reports on a medical philosophy that focuses on providing coordinated care and personal care to older patients, mostly indigent seniors. The paper examines Select Senior Clinic, a Texas facility that ascribes to the medical home concept.
Due to overriding concern for the health and safety of Jerry"s Kids, the Muscular Dystrophy Association (MDA) announced today that it is immediately canceling the remainder of its annual summer camp program because of the H1N1 virus.
The Economist examines schistosomiasis in China. The disease, which is also called snail-fever, is the "world"s second-most prevalent tropical disease after malaria, affecting 207 million people of whom 726,000 are Chinese, according to the most recent official figures, from 2004," the Economist reports.
Amarillo Biosciences, Inc. (ABI) (OTCBB: AMAR) announced that the screening of volunteers for inclusion in a Phase 2 clinical study of the company"s oral interferon product at the University of Western Australia is now complete. The investigators met their target of screening at least 200 healthy adults for participation in the trial. A total of 215 volunteers were evaluated and 134 of them have been enrolled into the study to date. About 90% of the screened subjects have been found to qualify for the study, so additional enrollments are expected over the next 2 weeks to bring the total number of study participants up to or above the targeted 160 subjects.
The fulfilment which so many people increasingly derive from competitive sports and endurance training comes with a real - even if rare - twist. Because, while most people will enjoy the benefits and pleasures of exercise, there are a few for whom regular athletic training will increase the risk of cardiac arrhythmias and even sudden death, especially among those in middle-age or with pre-existing cardiac diseases.
As President Obama prepares to sign a bill giving the Food and Drug Administration (FDA) oversight of the tobacco industry, a new study from Harvard School of Public Health (HSPH) researchers shows that tobacco manufacturers have continually changed the ingredients and the design of their cigarettes over time, even if those changes have exceeded acceptable product variance guidelines. The result, say the researchers, is that consumers who buy the same brand of product are not made aware of how that product has been altered and what effect those alterations might have on their levels of addiction or harm.
Ca2+/calmodulin-dependent protein kinase II alpha (CaMKII alpha) is an enzyme that adds phosphates to a variety of protein substrates to modify their functions. CaMKII alpha is enriched in the hippocampus, the memory center of the brain, and is believed to be an essential mediator of activity-dependent synaptic plasticity and memory functions. However, the causative role of the enzymatic activity of CaMKII alpha in such processes has not been demonstrated yet, because this enzyme has multiple protein functions other than the kinase activity. A Japanese research group, led by Dr Yoko Yamagata of the National Institute for Physiological Sciences, Japan, has successfully generated a novel kinase-dead mutant mouse of the CaMKII alpha gene that completely and exclusively lacks its kinase activity. They examined hippocampal synaptic plasticity and behavioral learning of the mouse, and found a severe deficit in both processes. They reported their findings in the Journal of Neuroscience, published on June 10, 2009.
Bio-Imaging Technologies, Inc., (NASDAQ: BITI) d/b/a BioClinica, a global provider of clinical trial services with more than two decades of experience and a thorough understanding of standards, is challenging the industry to increase standards implementation for clinical trials at the Drug Information Association (DIA) 45th Annual Meeting on June 21-25 in San Diego (booth #315). Standards support has quickly become a key focus for the life science industry to streamline the clinical trial process and reduce costs. However, the complexity of the task and the re requirements put implementing standards on the "someday list" for many companies.
Because of increased risk of complications from influenza, vaccination of adults and children with asthma is recommended by the Advisory Committee on Immunization Practices. The Healthy People 2010 Objectives call for annual influenza vaccination of at least 60% of adults aged 18-64 years with asthma. However, Centers for Disease Control and Prevention (CDC) investigators have determined that the vaccination levels among asthma sufferers falls well short of this guideline. The results of their study are published in the August 2009 issue of the American Journal of Preventive Medicine.
"Latest research raises important ethical issues concerning our care for patients with chronic consciousness disorders," said Professor Gustave Moonen (Liege, Belgium), past president of the European Neurological Society (ENS), at a press conference at the current ENS Congress. This major meeting in European neurology is gathering more than 2,900 experts from all over the world in Milan. "This is all the more important as studies have shown that more than a third of patients given an initial diagnosis of vegetative state or persistent vegetative state show minimal signs of consciousness under more detailed examination."
Amicus Therapeutics (Nasdaq: FOLD) announced it has commenced the U.S. registration Phase 3 trial with its investigational drug, Amigal(TM) (migalastat hydrochloride) for the treatment of Fabry disease. The Company has reached agreement with the U.S. Food and Drug Administration (FDA) on the key protocol design elements of the pivotal trial, including the use of the surrogate primary endpoint of the change in the amount of kidney interstitial capillary GL-3, the substrate that accumulates in the cells of Fabry patients. In addition, the FDA is in agreement that the Company is eligible to seek Accelerated Approval for Amigal according to Subpart H regulations. The Company has begun submitting the Phase 3 protocol to investigational sites worldwide and expects to begin the dosing of subjects in the second half of this year.
Last week the FDA knocked the wind out of asthmatics by requesting the manufacturers of Singulair, a popular leukotriene blocking asthma and allergy drug, to upgrade their warning against psychotic side effects. Further respiratory distress was imposed on Zicam users when the FDA also last week announced warnings that the drug may cause a loss of smell.
Providence Tarzana Medical Center on Friday became the first. hospital in the nation to use the latest generation in imaging - the Ziehm Vision RFD - in this case to aid a surgeon in opening the clogged carotid artery of a patient who had suffered a small stroke.
New research shows that physicians failed to report clinically significant abnormal test results to patients -- or to document that they had informed them -- in one out of every 14 cases of abnormal results. In some medical groups, the failure rate is close to zero; in others it is as high as one in four abnormal results.
Novexel, a speciality pharmaceutical company focused on the discovery and development of novel antibiotics designed to overcome the significant global problem of microbial resistance, announces that its two most advanced pipeline products NXL104 and NXL103 are the subject of four posters at the 19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). The ECCMID conference is taking place in Helsinki between 16th and 19th May 2009.
A new study in CMAJ (Canadian Medical Association Journal) reports that the rates of death and hospital admissions for cardiovascular disease declined thirty percent over a ten year period in Canada. The findings draw attention to successful efforts to prevent heart disease, the leading cause of death globally. But, for the first time, there is indication that more women than men are dying of cardiovascular causes.
South Dakota State University research shows that a child with leaner body mass, or muscle, builds bigger bones than a child who weighs the same but has a greater percentage of fat.
European Neurological Society
The results of current clinical trials on new substances for MS therapy are among the new research findings that are being discussed with particular interest at the ENS meeting. Professor Comi is part of an international research team presenting the latest results of a study involving the orally administered drug fingolimod that is still in the clinical trial state and yet to be approved. An earlier study showed that oral fingolimod reduced the annualizied relapse rate in MS patients by more than 50 percent versus placebo.
A new study from the US suggests that the less socially active an older person is, the higher the chances that their motor ability such as strength
House Democrats" health care bill draft released Friday is likely to survive relatively intact, "including a robust new Medicare-like public health plan that would compete with private companies in a national health insurance exchange," Roll Call reports.
The total cost for treating a child with autism can reach $5 million, but insurance companies rarely cover autism therapy and few states mandate it. CBS News reports that "an estimated one in every 150 children in America has autism and the number of reported cases is growing" while "parents are increasingly demanding that insurance companies cover the newest treatment."
Australia"s leading nutrition organisation, the Dietitians Association of Australia (DAA), has
The British Dental Association (BDA) has applauded the publication today of Professor Steele"s review of NHS Dentistry, and called on the Government to work constructively with patients and the profession on its findings. The BDA has also urged the Government to heed the report"s recommendation to pilot properly reforms it introduces as a result of this report.
The National Minority Quality Forum (NMQF) today launched an online tool that maps the prevalence of HIV and AIDS by county, age, gender and ethnicity in all 50 states, Washington, D.C., Puerto Rico and the U.S. Virgin Islands, the San Francisco Chronicle reports. The HIV/AIDS Atlas is based on 2006 data collected from states and cross-checked with CDC data. The NMQF partnered with George Washington University"s School of Public Health and Health Services to collect and analyze the data. Gary Puckrein, chief executive officer of NMQF, said the new tool will help improve data collection and analysis, prevention initiatives, early diagnosis and routine testing efforts in areas most affected by HIV/AIDS (Colliver, San Francisco Chronicle, 6/21).
On Wednesday, a national HIV testing campaign called "Don"t?Guess?Test!" is making a "controversial move" by distributing free HIV testing kits that have not been approved by FDA in the lead up to National HIV Testing Day on June 27, the Washington Business Journal reports. The kits have been clinically tested and are available in Africa, Asia and Europe, according to the Business Journal. Due to the sensitive nature of the non-FDA-approved kits, campaign officials are not disclosing how many tests will be distributed or the location of distribution at this time (Plumb, Washington Business Journal, 6/22).
Instead of responding to natural disasters after they happen, aid should be dedicated to helping countries prepare for future disasters, John Holmes, the U.N."s emergency relief coordinator, said Friday, Reuters reports. "You can"t stop the disasters happening but you can make an enormous difference to whether they kill people and, to some extent at least, have their livelihoods destroyed," Holmes said during a press conference in Geneva that came at the end of a week-long meeting that tackled ideas on how to best prepare poorer countries for natural disasters.
The National Organization for Women on Saturday during its annual conference elected Terry O"Neill as the group"s new president, the Indianapolis Star reports. O"Neill succeeds Kim Gandy, who has served two four-year terms as NOW president. The group has grown to include about 500,000 advocate members since its founding in 1966.During the conference, participants discussed a number of women"s rights issues, including same-sex marriage, equal pay and health insurance affordability. O"Neill raised the issue of "conscience" clauses, which allow health care workers to refuse to provide information or services on moral or religious grounds. O"Neill said, "Conscience clauses, where pharmacists refuse birth control sales because it"s against their conscience, must go. Guess what? Women have a constitutional right to birth control," adding, "There is no constitutional right to be a pharmacist" (Jacobs, Indianapolis Star, 6/21).O"Neill served as NOW"s vice president for membership from 2001 to 2005. She most recently served as chief of staff for a county council member in Montgomery County, Md. O"Neill in a prepared statement said that she is "honored and eager" to lead NOW (AP/Google.com, 6/21).
After the murder last month of Kansas abortion provider George Tiller, "there is a very real danger" that the availability of abortion later in pregnancy "will end in this country -- not after public deliberation, legislative debate and majority vote, but because antiabortion absolutists on the fringe have intimidated and blacklisted doctors and successfully threatened violence against them," Jim Buie, author of the blog The Buie Knife, writes in a Newsweek.com opinion piece. Buie writes that his parents in the early 1950s chose to institutionalize his three-year-old-brother, who was born with severe Down syndrome, after their attempts to care for him left them with "severe emotional distress" and unable "to meet the needs of their healthy children."Buie continues that he "cannot say that the option of a late-term abortion would have been the right one for my parents." However, "some of the arguments advanced by pro-life forces disturb me," he says, especially a "tendency to romanticize, sentimentalize and idealize life with a cute, forever-young Down-syndrome "angel child."" Buie adds, "It"s an argument I find off-putting, especially when it"s espoused by people who have never been through the wringer trying to care for a child whose disability level is on the most severe end of the scale." He continues, "At the same time, it is very disturbing that until recently, the majority of Down-syndrome fetuses were aborted without expectant mothers receiving proper information or support."Because of Tiller"s murder, it is "possible there won"t be any doctors in the country willing to perform" abortion later in pregnancy, "even if prenatal tests indicate severe retardation," according to Buie, who adds that this would mean that "domestic terrorism could win." He concludes, "It would mean that parents like my own would no longer have a choice, and would instead be forced to endure the same harsh realities that were present in the 1950s" (Buie, Newsweek.com, 6/17).
The muscle relaxer Botox has now been shown to positively affect the skin as well.
Women may be more susceptible to the lung damaging effects of smoking than men, according to new research by Inga-Cecilie Soerheim, M.D., and her colleagues from Channing Laboratory, Brigham and Women"s Hospital and University of Bergen, Norway.
A study published in the July issue of Anesthesiology offers perhaps the first estimation of how genomic copy number variation (CNV) can influence anesthetic sensitivity and the magnitude of this influence.
Appendicitis is the most common childhood surgical emergency, but the diagnosis can be challenging, especially in children, often leading to either unnecessary surgery in children without appendicitis, or a ruptured appendix and serious complications when the condition is missed. Now, emergency medicine physicians and scientists at the Proteomics Center at Children"s Hospital Boston demonstrate that a protein detectable in urine might serve as a "biomarker" for appendicitis. Their report was published online June 23 by the Annals of Emergency Medicine.
Judicial Watch, the public interest group that investigates and prosecutes government corruption, announced today that it has obtained records from the Food and Drug Administration (FDA) documenting 28 deaths in 2008 associated with Gardasil, the vaccination for human papillomavirus (HPV), up from the 19 deaths in 2007. The total number of Gardasil-related deaths is 47 since the vaccine was approved in 2006. Overall, the FDA documented 6,723 "adverse events" related to Gardasil in 2008, of which 1,061 were considered "serious," and 142 considered "life threatening."
Poorer countries in Africa, Asia and Latin America are far from ready to deal with an H1N1 pandemic, and will need help to develop stockpiles
Companies are being reminded of their duty to protect their workforce, especially workers from other countries, after a migrant worker employed at a pet bedding company suffered serious injuries in a shredder.
Health workers fail to understand the importance of sex for Tanzanian children
The Magnetic Resonance Center of the University Children"s Hospital Zurich has achieved a world first break through in MR-guided, non-invasive neurosurgery. Ten patients have been successfully treated by means of transcranial high-intensity focused ultrasound. This fully non-invasive procedure opens new horizons for neurosurgery and the treatment of different neurological brain disorders.
Pediatric researchers have identified hundreds of gene variations that occur more frequently in children with attention-deficit hyperactivity disorder (ADHD) than in children without ADHD. Many of those genes were already known to be important for learning, behavior, brain function and neurodevelopment, but had not been previously associated with ADHD.
Abbott announced that it has received CE Mark (Conformite Europeenne) for its next-generation XIENCE PRIME(TM) Everolimus Eluting Coronary Stent System for the treatment of coronary artery disease. The company plans to launch XIENCE PRIME in a broad size matrix with lengths up to 38 mm in Europe in the third quarter.
Researchers at The University of Texas School of Public Health have developed a game for HIV-positive youth, +CLICK, designed to reduce secondary transmission of the virus.
While suffering a major stroke at her home near Mena, Iva Sikes assumed the worst, not knowing that a University of Arkansas for Medical Sciences (UAMS)-led telemedicine program would provide her a complete recovery.
The London School of Hygiene & Tropical Medicine has won the Gates Award for Global Health, and will receive $1 million in prize money.
The Australian Medical Association will work with the Federal Government to ensure patients benefit from the introduction of new prescribing rights for nurse practitioners and midwives.
A Queensland University of Technology researcher is calling for volunteers to take part in a project examining the role of childhood visual experience on eye growth. Stephen Vincent, a practising optometrist, is conducting the research as part of his PhD and will spend the next 12 months examining volunteers with specific eye conditions such as amblyopia (lazy eye) and strabismus (turned eye).
More than 500 scientific abstracts to be presented across 20 types of
The Kansas Department of Health and Environment (KDHE) is reminding Kansans to protect themselves in hot summer temperatures.
The New Jersey Department of Health and Senior Services recently announced a fifth death of a New Jersey resident with novel H1N1 influenza.
What do a college of veterinary medicine and a cancer treatment and research center have in common? The answer may be as plain as the nose on your dog"s face. Researchers from North Carolina State University"s College of Veterinary Medicine and the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center are combining their expertise to pinpoint the cause of -- and improve treatments for -- non-Hodgkin lymphoma in human and canine patients.
The Washington Post reports many oral health professionals worry that dental issues have "a tenuous place at best in the national debate" regarding an overhaul of the health care system. Still, they emphasize that dental health is an integral part of health care and note the special burden untreated dental issues have on poor children. The paper also notes that "closing the gap between the worlds of dental care and medical care, with their separate histories and cultures, and their separate finance and delivery systems would be a formidable task."
Scientists at the University of Alberta have found that there are significant differences in the way our brains function depending on whether we"re early risers or night owls.
Young adults who are overweight or obese have an increased risk of pancreatic cancer, and being obese at an older age is associated with a lower overall survival rate for patients with pancreatic cancer, according to a study in the June 24 issue of JAMA.
Iron-deficiency anaemia (IDA) is commonly seen in women aged under 50 years. The diagnostic workflow in young women affected by IDA is not clearly established. The British Society of Gastroenterology recommends gastroscopy only in IDA women younger than 45 years presenting with gastrointestinal (GI) symptoms. However, symptoms are often mild and aspecific in IDA women and the gastroscopy is an invasive procedure associated with a high number of refusals. In a previous work on IDA premenopausal women, gastroscopy was performed in all patients, later deemed unnecessary in almost 30% of the studied women because these were affected only by menorrhagia.
Antibiotic prescribing for respiratory illnesses should be standardised across Europe to help reduce inappropriate prescribing and resistance, say experts in a study published on bmj.com.
Research presented by Bernard Casey of the University of Warwick"s Institute for Employment Research shows that work-related stress today damages national output even more than the loss to national output due to strikes at the peak of industrial unrest in the 1970s.
A common electrocardiogram (ECG) finding that has largely been considered insignificant may actually signal an increased risk of atrial fibrillation (a chronic heart rhythm disturbance), the future need for a permanent pacemaker and an increased risk for premature death. In their report in the June 24 Journal of the American Medical Association, researchers from Massachusetts General Hospital (MGH) and Boston University School of Medicine describe results of the first large-scale study looking at the significance of a prolonged PR interval in a general population.
Dr. Janet D. Latner, an Associate Professor of Psychology at the University of Hawai"i at Manoa, has co-authored an article in the July 2009 edition of the Journal of Sex & Marital Therapy on "Weight Stigma in Existing Relationships."
In order to recognize and encourage cutting-edge research in key areas of orthopaedic sports medicine, the American Orthopaedic Society for Sports Medicine (AOSSM) will present eight research awards and two grants during its Annual Meeting, July 9-12th in Keystone, Colorado. As a leader in orthopaedic sports medicine, AOSSM annually provides more than $150,000 to research initiatives and projects around the country. Highlights of this year"s award recipients include:
Genital warts are also called venereal warts or condylomata acuminate. Genital warts are one of the most common kinds of STDs (sexually transmitted diseases) or STIs (sexually transmitted infections). According to Medilexicon"s medical dictionary, a genital wart is "a contagious projecting warty growth on the external genitals or at the anus, consisting of fibrous overgrowths covered by thickened epithelium showing koilocytosis, due to sexual contact with infection by human papillomavirus; it is usually benign, although malignant change has been reported, associated with particular types of the virus."
Researchers at the University of Turin have launched a major initiative to prevent and
Avecia Biologics has announced it has received a Manufacturer"s Licence from the UK"s Medicines and Healthcare products Regulatory Agency (MHRA). The Licence authorises commercial manufacturing at the company"s Tees Valley, UK site and comes three months after the company successfully underwent its first FDA Pre-Approval Inspection.
One of every four American adults suffers from a silent condition known as pre-diabetes at a cost of more than $25 billion a year in increased medical costs, according to new data published today. And among the 180,000 pregnant women diagnosed with gestational diabetes, health care costs attributed to the condition are estimated at $623 million a year, a companion study showed.
Women who have migraines with aura may be more likely to have a stroke or heart attack than women who don"t have the condition, and the association varies by migraine frequency, according to research published in the June 24, 2009, online issue of Neurology®, the medical journal of the American Academy of Neurology. An aura is a visual or other sensory disturbance that occurs before the migraine starts, such as seeing bright lights.
A group led by Columbia University Medical Center"s Timothy Wang, M.D., has studied the role of Helicobacter infection in the development of stomach cancer and found that the hormone gastrin, which stimulates secretion of gastric acid, plays a key role in the development of Helicobacter-induced stomach cancer, and may have distinct effects on carcinogenesis in different parts of the stomach.
Iraqi health authorities confirmed yesterday that six people recently returned from the US have tested positive for H1N1 epidemic or swine flu,
The New York Times reports that it has obtained 10 memorandums prepared by conservative groups on President Obama"s possible choices to replace retiring Supreme Court Justice David Souter that outline how conservatives hope to frame the coming nomination debate. The memos focus on 10 female potential nominees. Although the groups have gathered information on about three dozen people, both liberals and conservatives expect that Obama will nominate a woman for the position.The memos analyze the possible nominees" records and dissect statements they have made that conservative groups find objectionable. The memorandum on Judge Diane Wood criticizes her as an "outspoken" supporter of "abortion, including partial-birth abortion." In addition, the memo on Judge Sonia Sotomayor says she is willing to expand rights in the Constitution past where the text allows, while the summary on Judge Kathleen Sullivan says she supports same-sex marriage.According to the Times, conservatives have acknowledged that Democrats" control of the Senate gives them little chance of defeating the nomination, but they still aim to mount a formidable debate. Conservative groups hope that rallying their supporters behind a common cause "could help refill depleted coffers and galvanize a movement demoralized by Republican electoral defeats," the Times reports. Gary Marx, executive director of the conservative Judicial Confirmation Network, said that donors have committed to contributing millions of dollars for advertisements on television, radio and the Internet. Richard Viguerie, a conservative fundraiser, said, "It"s an immense opportunity to build the conservative movement and identify the troops out there." Nan Aron, president of the liberal Alliance for Justice, said, "I think the mood and the politics of the country have passed [conservatives] by." According to the Times, liberal groups also have created a shared research pool for the coming debate (Savage, New York Times, 5/17).
Acucela, a clinical-stage biotechnology company focused on developing new treatments for blinding eye diseases, announced today that data on the company"s novel visual cycle modulator, ACU-4429, a potential oral treatment for dry age-related macular degeneration (AMD), will be featured at the Aegean Retina XI Meeting being held in Crete, Greece from July 3 to 5, 2009. Dry AMD is a leading cause of vision loss in people over the age of 50, yet there are no therapies currently approved to treat this condition.
Jazz Pharmaceuticals, Inc. (Nasdaq: JAZZ) and UCB (Euronext Brussels: UCB) announced today positive preliminary top-line results from the second of two Phase III clinical trials of sodium oxybate (JZP-6) for the treatment of fibromyalgia. Confirming the positive results from the first Phase III study, this international, placebo-controlled trial of sodium oxybate to treat fibromyalgia achieved its key endpoints. As in the first randomized, double-blind fibromyalgia study, sodium oxybate significantly decreased pain and fatigue and improved daily function and patient global impression of change. Sodium oxybate has not been evaluated by regulators for the treatment of fibromyalgia and is not approved for this use.
The emerging field of synthetic biology draws on a variety of technologies, including genetic engineering and nanotechnology, to engineer biological systems to perform novel tasks. As the science and its applications develop, instead of creating a "new kind" of ethics for each new techno-scientific arena, a comprehensive approach is needed to address ethical and social issues of emerging technologies as a whole, according to a report by Erik Parens, Josephine Johnston, and Jacob Moses of The Hastings Center. Synthetic biology promises significant advances in areas such as biofuels, specialty chemicals, agriculture, and medicine but also poses potential risks.
Seventy-six percent of U.S. residents believe that abortion should be legal, a finding in keeping with public opinion over the past three decades, according to a Gallup poll released on Saturday, the AP/Boston Globe reports (AP/Boston Globe, 5/16). However, 51% of respondents identified themselves as "pro-life," while 42% said they are "pro-choice" (Gallup poll, 5/16). The finding marks the first time since Gallup began asking about abortion rights in 1995 that a majority of respondents said they consider themselves "pro-life" (Nadeau, Boston Herald, 5/16). Last year"s poll showed that 50% of respondents consider themselves "pro-choice," compared with 44% who said they are "pro-life" (Abcarian, Los Angeles Times, 5/16).The new poll found that 53% of respondents believe abortion should be legal under some circumstances, 23% believe it should be legal under any circumstances and 22% believe it should be illegal under any circumstances (Boston Herald, 5/16). The percentage of respondents who oppose abortion rights in all cases rose slightly from last year, while those who support abortion rights in all cases decreased slightly. The Los Angeles Times reports that the percentage of respondents who oppose abortion rights in all circumstances and those who support abortion rights in all circumstances is "a virtual tie." The results have a margin of sampling error of plus or minus three percentage points.Respondents who labeled themselves as moderates and Republicans accounted for most of the change in views compared with past polls, as Democrats" views remained consistent with previous years, according to the Los Angeles Times. Gallup in its analysis wrote that it is "possible" that President Obama "has pushed the public"s understanding of what it means to be "pro-choice" slightly to the left, politically" (Los Angeles Times, 5/16). The survey was conducted between May 7 and May 10 (AP/Boston Globe, 5/16).Nancy Keenan, president of NARAL Pro-Choice America, said, "I am pretty confident that Americans really don"t want Roe v. Wade overturned." She added that the increase in respondents identifying as "pro-life" does not "square with what has happened in the last several elections," noting that voters have rejected several antiabortion-rights ballot measures in South Dakota, California, Oregon and Colorado since 2005. However, Charmaine Yoest, president of Americans United for Life, said, "It tracks pretty much with what we"ve always known: People generally are pro-life depending on how you ask the question" (Los Angeles Times, 5/16).
Experts have long suspected that part of the process of turning fleeting short-term memories into lasting long-term memories occurs during sleep. Now, researchers at the RIKEN-MIT Center for Neural Circuit Genetics of MIT"s Picower Institute for Learning and Memory have shown that mice prevented from "replaying" their waking experiences while asleep do not remember them as well as mice who are able to perform this function.
Scientists at The Institute of Cancer Research (ICR) and The Royal Marsden Hospital, working with pharmaceutical company AstraZeneca, have completed a Phase I clinical trial demonstrating the great promise of a completely new type of cancer treatment. The results are announced today in The New England Journal of Medicine.
Nearly 90 percent of morbidly obese patients with Type 2 diabetes experienced diabetes resolution within the first year of gastric bypass surgery and about 60 percent remained diabetes-free five to 16 years later, according to a new study presented today at the 26th Annual Meeting of the American Society for Metabolic & Bariatric Surgery (ASMBS).
"As President Obama"s effort to overhaul the health care system seems to hit one roadblock after another in Congress, he is counting on Senator Max Baucus [D-Mont.], a political shape-shifter and crafty deal maker who is not fully trusted by either party, to help him clinch his top domestic priority," the New York Times reports in a profile of the Senate Finance Committee leader. Sen. Chris Dodd, D-Conn., has been unable to garner GOP support. Obama"s preferred health leader, Tom Daschle, dropped out of the Obama team because of tax problems and highly partisan House Democrats have failed to work with Republicans, leaving the task of ushering a bill through the legislative process largely to Baucus.
Figures from the British Institute for Anger Management reveal that the UK already has the worst road rage figures of any European nation, with 80% of drivers saying they"ve been involved in an incident and 1 in 4 admitting to committing an act of road rage themselves. Men are three times more likely to commit an act of aggression than women and over 60% of drivers say they have been intimidated by aggressive tailgating.
Advances in weight-loss surgery have made it as safe as any routine surgical procedure, according to a Duke University Medical Center researcher who reviewed data from nearly 60,000 patients and found it resulted in low complication and mortality rates.
Researchers from the University of California, Davis have developed a specific and quantitative means of measuring levels of the fragile X mental retardation 1 (FMR1) protein (FMRP), which is mutated in fragile X syndrome. The related report by Iwahashi et al, "A quantitative ELISA assay for the fragile X mental retardation 1 protein," appears in the July 2009 issue of the Journal of Molecular Diagnostics.
A group led by Dr. Alberto Bardelli at The University of Turin Medical School reports that myoglobin may protect against the stresses of tumor growth. This study can be found in the July 2009 issue of the American Journal of Pathology.
South London Healthcare NHS Trust (SLHT) is delighted to announce a new partnership with the NHS Institute for Innovation and Improvement as part of the trust"s drive for
Research co-led by an academic at the University of Hertfordshire, concludes that Cognitive Behavioural Therapy (CBT) is of no value in schizophrenia and has limited effect on depression. Professor Keith Laws, at the University"s School of Psychology, is one of the lead authors on a paper entitled: Cognitive behavioural therapy for major psychiatric disorder: does it really work? A meta-analytical review of well-controlled trials, which has just been published online in the journal Psychological Medicine. The paper reviews the use of CBT in schizophrenia, bipolar disorder and major depression.
Finalising a review of the safety and efficacy of
A multi-center clinical trial led by a Riley Hospital for Children endocrinologist has found that inhaled growth hormone (GH) is well tolerated by children with GH deficiency and that this easy-to-use method can, over a one-week period, safely deliver GH to the blood stream. In addition to having implications for those who need GH, this first pediatric study of administering it through the lungs may also help researchers interested in using this convenient method for effectively delivering other types of medications to children.
Strep throat is a sore throat caused by bacteria known as Streptococcus pyogenes, or group A streptococcus. Sore throat is a term for any situation where the throat feels scratchy, tender, and possibly painful. Strep throat is a type of sore throat. Sore throat may be caused by bacteria or viruses, while strep throat is only caused by bacteria. The term strep throat is more commonly used in the USA and Canada, compared to other English speaking countries. Strep throat may also be referred to as Streptococcal pharyngitis or streptococcal sore throat.
Insmed Inc. (Nasdaq: INSM), a biopharmaceutical company, announced results from its exploratory U.S. Phase II clinical trial evaluating IPLEX(TM) (mecasermin rinfabate) in patients with myotonic muscular dystrophy ("MMD"). The randomized, double-blind, placebo-controlled Phase II trial conducted in 13 centers across the U.S. enrolled 69 patients with MMD, for a six-month period. As this was an exploratory trial, a primary endpoint was not pre-defined. The trial explored measures of endurance, using the six-minute walk test, muscle function and strength, cognitive function, gastrointestinal function, pain, quality of life, insulin sensitivity, lipid metabolism, and safety and tolerability of IPLEX(TM).
More pieces in the complex autism inheritance puzzle are emerging in the latest study from a research team including geneticists from The Children"s Hospital of Philadelphia, the University of Pennsylvania School of Medicine and several collaborating institutions. This study identified 27 different genetic regions where rare copy number variations missing or extra copies of DNA segments were found in the genes of children with autism spectrum disorders (ASDs), but not in the healthy controls. The complex combination of multiple genetic duplications and deletions is thought to interfere with gene function, which can disrupt the production of proteins necessary for normal neurological development.
Kidney injury that can arise after undergoing certain medical imaging procedures increases a patient"s risk of having a stroke or heart attack over the next year or two, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The findings indicate that seemingly minor and reversible kidney damage from these common clinical procedures is a serious health threat.