Diagnostics
Statement of Charles D. Connor, American Lung Association President and CEO:
As advocacy groups with a stake in health reform take positions in the health reform debate, their battle lines don"t necessarily observe the boundaries of a given sector, industry or professional affiliation. "Business is far from unified in its lobbying efforts for health-care reform," McClatchy/Chicago Tribune reports. "The disparity dilutes its power and may contribute to a plan no faction wants -- or no plan at all."
Trinity Biotech plc (NASDAQ: TRIB), a leading developer and manufacturer of diagnostic products for the point-of-care and clinical laboratory markets, announced it has submitted its CLIA application for its TRI-stat™ point-of-care HbA1c product to the FDA.
More people would benefit and it would be more cost effective if HIV treatment with antivirals started earlier in countries like South Africa where medical res are limited, said researchers.
Ducking a punch or a thrown spear calls for the power of the human brain to process 3-D motion, and to perceive an object (whether it"s offensive or not) moving in three dimensions is critical to survival. It also leads to a lot of fun at 3-D movies.
On the occasion of World Hepatitis Day and on the eve of the European Parliament elections, healthcare professionals and patients call on EU decision-makers to make the next 5 years about protecting the liver!
Cardiovascular disease is increasing in adults under 50 and those of lower socioeconomic status, despite recent trends which show that cardiovascular disease is declining in Canada overall, say researchers at the Peter Munk Cardiac Centre. Untreated cardiovascular disease can lead to heart failure, coronary artery disease and death, and is the most common cause of hospitalization in North America.
Every time a neuron sends a signal - to move a muscle or form a memory, for example - tiny membrane-bound compartments, called vesicles, dump neurotransmitters into the synapse between the cells. Researchers report that this process, which is fundamental to the workings of the nervous system, relies on a simple mechanical reality: Tension in the axon of the presynaptic neuron is required.
California and Arizona researchers have identified a gene variant that carries nearly twice the risk of developing an increasingly common type of blood cancer, according to a study published online by the science journal Nature Genetics.
In a major advance in obesity and diabetes research, Yale School of Medicine scientists have found that reducing levels of a key enzyme in the brain decreased appetites and increased energy levels.
TCGRx (TCG), an industry leader in automation and design services for pharmacy markets across the U.S., announced today the launch of the C-Ray Electronic Pill Counter in the retail pharmacy market.
Scientists at the U.S. Department of Energy"s (DOE) Lawrence Berkeley National Laboratory have developed a fast and efficient way to determine the structure of proteins, shortening a process that often takes years into a matter of days.
For decades, scientists assumed that the ovary alone produced steroid hormones during pregnancy. In a new study in mice, however, researchers demonstrate that once an embryo attaches to the uterine wall, the uterus itself actually synthesizes the estrogen needed to sustain the pregnancy.
Compared with patients with moderately controlled glucose levels, diabetic patients who have heart failure and either too high or too low glucose levels may be at increased risk of death, said researchers at Baylor College of Medicine in a report published in the current issue of Journal of the American College of Cardiology.
MYCAMINE (micafungin), the newest echinocandin, is now available in thirteen European markets: UK, Greece, Czech Republic, Slovakia, Nordic region*, Spain, Germany, Ireland and France following its EU approval in April 2008.
King"s Patient Safety & Service Quality Research Centre (King"s PSSQ) is taking the lead on a major new international research project on quality and safety in European hospitals. A grant of 3 million Euros has been secured for the work (subject to contract), which will also involve the PSSQ Research Centre at Imperial College and partners from Sweden, the Netherlands, Portugal and Norway*.
Two Southampton surgeons who contributed to the development of keyhole surgery to treat early stage lung cancer have been internationally commended for their work.
The former Ghanaian president, John Kofi Agyekum Kufuor, has
A significant part of the question of what causes mitral valve disease in dogs, giving scientists and medical experts clues into new possible ways to treat or prevent the disease, may have been solved by a Colorado State University veterinarian. The discovery refutes the current believe that mitral valve disease, the top heart disease in dogs, is inevitable as a part of aging in pets.
The risk of developing breast cancer due to taking hormone replacement therapy appears to be the same for women with a family history of the disease and without a family history, a University of Rochester Medical Center study concluded.
Across the state of Maryland, there are now doctors and nurses, freshly trained in pediatric dental health care, who can help stem an alarming number of 3-year-old children who arrive for their first dentist visit with teeth "just melting away."
University of Utah School of Medicine researchers and their colleagues at University of Texas (UT) Southwestern Medical Center have found strong evidence that abnormal calcium signaling in neurons may play an important role in the development of spinocerebellar ataxia type 2 (SCA2), a disorder causing progressive loss of coordination, speech difficulty, and abnormal eye movements. Their findings are published in the July 27, 2009 issue of Journal of Neuroscience.
Two large US studies published in a leading journal this month support the already substantial body of evidence that shows choosing to follow a
The Escambia County Health Department announced that a sentinel chicken from the Riverview
"Digital medical records could cut down on office visits," and maybe even health care costs, Marketplace reports. "But for doctors, going electronic could be complicated and expensive. And nothing at all like what they learned in medical school." Relatively few doctors have made the switch so far, though new government incentives, funded by the stimulus bill, could shift the industry into gear. The doctors who have pioneered e-health have confronted a newish industry with few standards. One recalled that his early adoption of the records in 2003 was "a disaster," though he is now touted as an example for other practices (Carroll, 7/20).
Vesselplasty, a new minimally invasive procedure, increases mobility and reduces pain and the need for pain killers in patients with vertebral compression fractures (VCFs), according to a study performed at the Hospital Universitario Doctor Peset, Valencia, Spain. Vesselplasty is a new alternative to vertebroplasty and kyphoplasty-two conventional VCF treatment methods. Vesselplasty solves the problem of leakage of cement out of the vertebral body which can happen during both vertebroplasty and kyphoplasty," said Lucia Flors, MD, lead author of the study.
The disease onchocerciasis, also known as river blindness, can be eliminated using drugs, according to a WHO study, BBC reports. The disease, which infects about 37 million people worldwide, is caused by a "nematode worm that can live inside the human body for years" and is transmitted to people through the bite of a black fly, the news service writes. The worms spread through the body and when they eventually die, the human immune system "reacts fiercely," which "destroys living tissue - especially the eye," according to BBC (7/21).
Commenting on the final biennial report from the Mental Health Act Commission released by the Care Quality Commission, Mental Health Network director Steve Shrubb said:
New research indicates that screening children for symptoms of depression, the most common mental health disorder in the United States, can begin a lot earlier than previously thought, as early as the second grade.
A pioneering University of Wolverhampton lecturer has won a ÷£25,000 grant to research the healing effect of sugar on cuts and wounds.
Three quarters of cancer patients say that the disease has affected their sex lives, according to a new survey by Macmillan Cancer Support, yet only a third of them said they had been spoken to about the issue by a health professional.
Planarian flatworms are only a few millimeters up to a few centimeters in length, live in freshwater and are the object of intense research, because they possess the extraordinary ability to regenerate lost tissue with the help of their stem cells (neoblasts) and even grow an entirely new worm out of minute amputated body parts. Now researchers from the Max DelbrÃøck Center in Berlin, Germany together with researchers in the US and Canada present the first comprehensive catalogue of small RNAs of planaria, elements that regulate gene expression. They also have identified small RNAs which may play a role in regeneration and stem cell function, Nikolaus Rajewsky from the MDC points out (PNAS, Early Edition)*.
Columbia University Medical Center"s Jeffrey A. Lieberman, M.D., a renowned expert in the field of schizophrenia, has been selected by the National Institute of Mental Health (NIMH) of the National Institutes of Health as principal investigator of a nationwide effort to develop an optimal early intervention strategy for treating people experiencing a first episode of the psychotic symptoms of schizophrenia.
A research published ahead of print in the Archives of Disease in Childhood reports that every hour of the day children are inactive adds three minutes to the time it takes them to fall asleep.
Schering-Plough announced that a New Drug Application (NDA) for a fixed-dose combination of mometasone furoate and formoterol fumarate has been filed in the United States and accepted for review by the U.S. Food and Drug Administration (FDA). Schering-Plough is seeking marketing approval from the FDA of the mometasone furoate/formoterol fumarate combination for the maintenance treatment of asthma in patients 12 years of age and older.
A major new study released today by Americans for Insurance Reform finds that premiums and claims for doctors both have dropped significantly in recent years while the medical malpractice insurance industry is enjoying remarkable profits in light of the global economic collapse. It concludes that further limiting the liability of negligent doctors and unsafe hospitals is not only unjustified, but also would have almost no impact lowering this country"s overall health care expenditures.
Johns Hopkins researchers have developed a novel way to monitor in real time the behavior of the TB bacterium in mouse lungs noninvasively pinpointing the exact location of Mycobacterium tuberculosis. The new monitoring system is expected to speed up what is currently a slow and cumbersome process to test the safety and efficacy of various TB drug regimens and vaccines in animals. Plans are already under way for developing a similar system to monitor TB disease in humans.
An exploratory study to be published in BJOG: An International Journal of Obstetrics and Gynaecology, has shown that women going into early preterm labour (before 34 weeks gestation) have low-levels of progesterone in their saliva as early as 24 weeks, and that moreover, these levels fail to rise during pregnancy in the normal way. This offers the possibility of developing a simple, non-invasive test to identify women at increased risk of delivering early.
Your favourite painting could reveal a lot about your personality, this is a conclusion of a study published today, 23rd July 2009 in the British Journal of Psychology, which found that people"s preferences for painting genres is linked to key personality traits.
American Indian teenagers become parents at twice the rate of other American teenagers. Many of these teens have greater environmental and behavioral challenges associated with living on reservations, including higher rates of poverty, increased rates of unemployment and school drop-out, higher rates of alcohol and drug abuse, impaired access to healthcare, as well as increased risk of domestic violence and suicide over the general population.
"A bitter Congressional fight over the cost of superexpensive biotechnology drugs has come down to a single, hotly debated number: How many years should makers of those drugs be exempt from generic competition?" The New York Times reports. "At issue are such drugs as Biogen Idec"s Avonex, for multiple sclerosis, which can cost more than $20,000 a year; Genentech"s Avastin for cancer, which can cost more than $50,000; and several Genzyme drugs for rare diseases that can cost $200,000 a year or more. ò€¦ Because they are hard to copy exactly, they have not been subject to the generic competition that eventually knocks down the price of drugs like Lipitor and Prozac."
"Nationally, about a quarter of all residency graduates began their medical training abroad. And in primary care - where there is a national shortage of physicians - more than half of all graduates are immigrants," The Concord Monitor reports. "New Hampshire"s primary care doctors are aging, and as they retire, recruiters said they will increasingly be replaced by physicians who began their training outside the country."
During the 5th International AIDS Society (IAS) Conference on HIV Pathogenesis, Treatment and Prevention meeting in Cape Town, South Africa, scientists "renewed the call for more immediate and urgent effort to be directed towards HIV prevention amid the dominance of treatment interventions and the world-wide search for a quick fix vaccine, which many agree, is years away," Health-e/allAfrica.com reports (Thom, 7/22).
The U.N. on Tuesday said "it is running a record funding-shortfall of $4.8 billion for its aid operations in 16 crisis-ridden countries" and has received "less than half of the $9.5 billion it needs to carry out it humanitarian operations this year," VOA News reports (Schlein, 7/21).
Results show percutaneous mitral repair using the MitraClip(R) system in symptomatic high-risk surgical patients with either functional mitral regurgitation (FMR) or degenerative mitral regurgitation (DMR) improves patient clinical status. The results from the 78 patient EVEREST II High Risk Registry demonstrated improvement in left ventricular function and reduced hospitalization for congestive heart failure for both MR groups at twelve months. Additionally, a reduction in mortality compared to the predicted mortality risk of surgery was reported for the registry. The results of the High-Risk Registry were presented at the third annual meeting of EuroPCR, the official congress of the European Association of Percutaneous Cardiovascular Interventions (EAPCI).
Researchers at the University of California, Berkeley, have developed a "prototype camera-phone mounted with a microscope" that can "magnify and photograph blood or saliva samples" for diagnosing diseases, the Canadian Press/Google.com reports. A report on the device was published on Wednesday in the journal PLoS One. The prototype, called CellScope, would enable "disease screening and diagnosis in the field where specialized clinical microscopy laboratories aren"t available, including in underdeveloped countries," according to the news service (Ubelacker, 7/21).
Rush University Medical Center and surgical robotics company Prosurgics announce the completion of the first colorectal surgeries in the U.S. using the FreeHand® laparoscopic camera controller.
Miltenyi Biotec announces the worldwide and exclusive release of Myelin Removal Beads. Myelin is a specialized membrane which ensheathes and insulates axons in the peripheral and central nervous system. During preparation of single-cell suspensions, myelin membrane fragments represent the major contaminant. "When dissociating adult neural tissue, usually less than 5 percent of the cell suspension consists of cells. The rest corresponds to cell debris", explains Dr. Rebecca Biloune, Product Manager for Neural Research Products at Miltenyi Biotec. "Removal of myelin leads to higher purity and recovery of target cells."
Boosting the number of practice nurses who work with GPs would help improve patient access to care, the AMA said today.
Fecal incontinence (FI) is a normal part of aging, or the perception that no treatment is available. Doctors may fail to comprehend patient hints about diarrhea and FI or may be reluctant to ask about fecal leakage, perhaps because of their own embarrassment or the perception that FI is a trivial concern.
Illumina (NASDAQ:ILMN) announced that the Genomic Medicine Institute (GMI) at Seoul National University College of Medicine in Korea, purchased seven additional Illumina Genome AnalyzerIIx sequencing systems, expanding the capacity of their recently established Asian Genome Center to 10 Illumina sequencing systems.
A research consortium based at Massachusetts General Hospital (MGH) has been awarded $15 million from the National Institute of Allergy and Infectious Diseases to investigate how the hepatitis C virus (HCV) resists suppression and clearance by the immune system. The five-year grant will support a Cooperative Center for Translational Research in Human Immunology, which also will focus on how some individuals successfully recover from HCV while the infection becomes chronic in most of those infected, with a special emphasis on immunological events in the liver as the site of HCV replication.
The recent H1N1 flu outbreak served as a genuine test of our national public health system"s ability to respond to an emerging public health threat and experts are cautioning that a more severe outbreak could occur in the fall of 2009. Leaders from some of the nation"s foremost public health and medical associations will conduct a briefing for staff members from House and Senate offices on Thursday, May 21, 2009. Speakers will focus on the status of the current public health workforce and efforts needed to sustain workforce capacity to respond to emerging infectious diseases.
The National Institute for Health and Clinical Excellence
Dr Sam Cartwright-Hatton from the University of Manchester has won this year"s May Davidson Award. The award is made each year by the British Psychological Society"s Division of Clinical Psychology to someone who has made an outstanding contribution to the development of clinical psychology within the first 10 years of their career.
Earlier this month the University of Wisconsin Cancer Center Riverview became the first medical facility in the world to treat patients with a breakthrough treatment of skin cancer. Located within Riverview Hospital, Wisconsin Rapids, the UW Cancer Center Riverview is the first to treat skin cancer patients with the FDA-cleared Axxent(R) Electronic Brachytherapy System from Xoft, Inc. Electronic Brachytherapy, eBx(TM) , delivers a high therapeutic dose to a cancer tumor while sparing nearby normal tissue by using a miniaturized X-ray rather than radioactive isotopes.
The androgen receptor a protein ignition switch for prostate cancer cell growth and division is a master of adaptability. When drug therapy deprives the receptor of androgen hormones, thereby halting cell proliferation, the receptor manages to find an alternate growth route. A new study by Dana-Farber Cancer Institute and Ohio State University scientists demonstrates how.
Human cells are able to secrete a cancer-killing protein, scientists at the University of Kentucky"s Markey Cancer Center have found.
AlphaRx, Inc. (OTCBB: ALRX) announced positive preclinical results which demonstrated that an inhaled tobramycin nanoparticle (Zysolin(TM)) formulation was a more effective treatment in animal models of acute Pseudomonas aeruginosa pneumonia when compared to inhaled and injected conventional tobramycin solutions. The data was presented recently in an oral podium session at the 36th Annual Meeting and Exposition of the Controlled Release Society in Copenhagen, Denmark.
A first-of-its-kind RAND Corporation study has linked the rapid growth in health care costs in the United States with job losses and lower output among industries that commonly provide workers with health insurance.
Sen. Lindsey Graham (R-S.C.) on Wednesday said he intends to vote for Supreme Court nominee Sonia Sotomayor, making him the fifth Republican senator to endorse the nominee, USA Today reports. Meanwhile, Senate Minority Whip Jon Kyl (R-Ariz.) became the 10th Republican to say that he will vote against her confirmation. During Sotomayor"s confirmation hearings last week, both Graham and Kyl "grilled her extensively," USA Today reports (Kiely/Brettschneider, USA Today, 7/23). According to Politico, Republicans privately estimate that Sotomayor could receive upward of 70 votes (Kady, Politico, 7/23). The Senate Judiciary Committee is scheduled to vote on the nomination Tuesday, followed by a full Senate vote late next week or the first week of August (Stanton, Roll Call, 7/22).According to CQ Today, Graham"s support could encourage other conservatives to back Sotomayor (Perine, CQ Today, 7/22). Graham said that Sotomayor "is definitely more liberal" than any Supreme Court nominee a Republican president would have chosen but that she also is "one of the most qualified" nominees in decades. He added, "I do believe that elections have consequences, and it"s not like we hid from the American people during the campaign that the Supreme Court nomination was at stake. The American people spoke" (USA Today, 7/23). Graham also said that he believes that Sotomayor "follows precedent" and "would not be an activist judge" (CQ Today, 7/22). He continued, "On balance, I do believe that the court will not dramatically change in terms of ideology with her selection," adding, "On some issues, quite frankly, (she) may be more balanced in her approach" (Hirschfeld Davis, AP/Boston Globe, 7/22).Kyl said, "Unfortunately, I have not been persuaded that Judge Sotomayor is absolutely committed to setting aside her biases and impartially deciding cases based upon the rule of law," adding, "And I cannot ignore her unwillingness to answer senators" questions straightforwardly" (Politico, 7/23).Broadcast Coverage NPR"s "All Things Considered" on Wednesday reported on Graham"s support of Sotomayor (Shapiro, "All Things Considered," NPR, 7/22).
Three prominent figures in the field of neuromuscular disease research have been re-elected to national leadership positions with the Muscular Dystrophy Association (MDA).
"For many of the 60 million people living in rural America, inadequate and unaffordable healthcare is an immediate and growing problem," Reuters reports. "Reform is a big deal here. We"re on the edge," said Brian Wolfe, an Iola [Kansas] family doctor. Half his patients rely on government aid for the poor and elderly and some who need care don"t seek it because they can"t payò€¦. Rural residents are heavily represented among the 46 million Americans lacking health insurance. Many are too poor to pay for a doctor"s visit and too far from cities to reach emergency rooms and free clinics. Additionally, rural residents are disproportionately losing jobs and insurance or their seeing benefits cut as employers fire workers and cut costs in the continuing recession. When rural residents do seek care, many find long lines for a shrinking number of primary care physicians and specialists."
Ovulation is one part of the female menstrual cycle whereby a mature ovarian follicle (part of the ovary) discharges an egg (also known as an ovum, oocyte, or female gamete). It is during this process that the egg travels down the fallopian tube where it may be met by a sperm and become fertilized.
By conducting a mammogram, a low-dose x-ray of the breasts, doctors can identify cancerous tumors well before a woman even feels a lump. According to the American Cancer Society, "Finding small breast cancers early by a screening mammogram greatly improves a woman"s chance for successful treatment."
A San Mateo County, Calif., program that provides in-home case management services for people living with HIV/AIDS, as well as other programs that assist people living with the virus, could be eliminated, forcing patients to obtain more expensive outpatient care, if proposed state budget cuts are approved, the San Francisco Examiner reports. John Conley, director of public health programs for San Mateo County, said case management services are alternatives to hospitalization or nursing facility care, which are more expensive. "Additionally, the state"s AIDS office will not allow municipalities to make reductions to case management activities or other requirements such as client/staff ratios, according to county officials," the Examiner reports. Conley said, the state is paying half the costs of the program, but the program is "becoming very, very expensive to run" (Koskey, 7/23).
Uncooked meat products enhanced with food additives may contain high levels of phosphorus and potassium that are not discernable from inspection of food labels, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). This can make it difficult for people to limit dietary phosphorus and potassium that at high levels are harmful to kidney disease patients.
Case Western Reserve University School of Medicine has received a $3.7 million grant from the National Institutes of Health to determine if painful bladder syndrome may be caused by abnormalities in the autonomic nervous system rather than in the bladder itself.
The Natural Products Association (NPA) announced that Daniel Fabricant, Ph.D., has been appointed interim executive director and CEO of the organization effective August 3. Fabricant has served as vice president of scientific and regulatory affairs with NPA since December of 2004. As was previously announced, David Seckman, who has headed the association for more than nine years, will be leaving at the end of the month to lead the Food Processing Suppliers Association.
The U.S. Department of Energy"s Brookhaven National Laboratory and Hybridyne Imaging Technologies, Inc., of Toronto, Canada, have won a 2009 R&D 100 Award for developing a compact gamma camera for high-resolution imaging of prostate cancer. The camera system, called ProxiScan, is a nuclear medical instrument that can localize cancer tissue in the prostate gland in detail at an early stage, which is important for the successful diagnosis and early treatment of the potentially deadly disease.
Much as meteorologists predict the path and intensity of hurricanes, Indiana University"s Alessandro Vespignani believes we will one day predict with unprecedented foresight, specificity and scale such things as the economic and social effects of billions of new Internet users in China and India, or the exact location and number of airline flights to cancel around the world in order to halt the spread of a pandemic.
In a paper publishing online July 23 in Cell Stem Cell, a Cell Press journal, Dr. Shaorong Gao and colleagues from the National Institute of Biological Sciences in Beijing, China, report an important advance in the characterization of reprogrammed induced pluripotent stem cells, or iPSCs.
Orexo"s (STO:ORX) partner in Japan, Kyowa Hakko Kirin, has obtained positive phase III results in Japan for KW-2246, which is approved for the treatment of breakthrough pain in cancer patients and marketed under the brand AbstralTM in Europe. Kyowa Hakko Kirin will now proceed with preparations for a new-drug application for KW-2246 in Japan for use in continuous pain management of acute cancer pain (breakthrough pain).
Two new studies reveal a way to increase the body"s appetite for gobbling up the cancer stem cells responsible for acute myeloid leukemia (AML), a form of cancer with a particularly poor survival rate. The key is targeting a protein on the surface of those cells that sends a "don"t eat me" signal to the macrophage immune cells that serve as a first line of defense, according to the reports in the July 24th issue of the journal Cell, a Cell Press publication.
As part of its continuing engagement in global health issues, Yale University"s Global Health Leadership Institute is partnering with Tsinghua University to launch a four-year leadership development program in healthcare management for women in China. The effort is part of the 10,000 Women initiative, a program launched by Goldman Sachs to provide business and management education to women around the world. The program is based on research from Goldman Sachs, the World Bank, and others which found that investments in women can lead to significant economic and social returns.
Aradigm Corporation (OTCBB:ARDM) (the "Company") announced it received clearance from the U.S. Food and Drug Administration (FDA) for its inhaled liposomal ciprofloxacin Investigational New Drug (IND) application. The initial clinical protocol under this IND is an international, randomized, double-blind, placebo-controlled Phase IIb study designed to evaluate the Company"s inhaled liposomal ciprofloxacin in patients with non-cystic fibrosis bronchiectasis (BE). This orphan drug condition is a chronic severe respiratory disease and there is currently no drug specifically approved for its treatment in the U.S.
Cyberonics, Inc. (Nasdaq: CYBX) announced that the U.S. Food and Drug Administration ("FDA") has approved the company"s proposal to amend the protocol of its D-21 post-approval dosing study in depression patients treated with VNS Therapy(TM).
Roche announced results from the international phase III study NO16968 (XELOXA), investigating oral Xeloda in combination with intravenous oxaliplatin (XELOX) immediately after surgery, which show that patients with colon cancer taking XELOX live disease free for longer compared to those taking the commonly used intravenous chemotherapy combination 5-fluorouracil/leucovorin (5-FU/LV). The data prove that XELOX is superior to 5-FU/LV in terms of the time patients live without their cancer being detectable.
At 96-week follow up, data from the MERIT ES analysis show that treatment-naç¯ve HIV patients taking Celsentri/Selzentry (maraviroc), in combination with Combivir® (zidovudine/lamivudine) experienced comparable virologic suppression to undetectable levels and significantly greater increases in CD4 T-cell count through 96-weeks, compared to patients taking efavirenz in combination with zidovudine/ lamivudine. The data also show the favorable tolerability of Celsentri/Selzentry, which was associated with fewer discontinuations due to adverse events.1
UroToday.com - In the online edition of the BJU International, Dr. Richard Stock and colleagues from Mt. Sinai School of Medicine in New York reported on their outcomes using combined radiotherapy approach to men with high-risk prostate cancer (CaP).
The number of human cases of pandemic (H1N1) 2009 is still increasing substantially in many countries, even in countries that have already been affected for some time. Our understanding of the disease continues to evolve as new countries become affected, as community-level spread extends in already affected countries, and as information is shared globally.
Astigmatism is an eye condition with blurred vision as its main symptom. The front surface of the eye (cornea) of a person with astigmatism is not curved properly - the curve is irregular - usually one half is flatter than the other - sometimes one area is steeper than it should be.
Abortion opponent Rep. Tim Ryan (D-Ohio) and abortion-rights supporter Rep. Rosa DeLauro (D-Conn.) held a press conference on Thursday to announce a bill that aims to reduce the need for abortion by preventing unintended pregnancies, among other proposals, the New York Times" "The Caucus" reports. The bill -- crafted in part by the centrist group Third Way -- would increase access to contraceptive services, sex education, health care coverage for pregnant women and children, and adoption. It also would expand access to comprehensive sex education and adoption programs.The bill has the support of abortion-rights groups like the Planned Parenthood Federation of America and NARAL Pro-Choice America, both of which had representatives at the press conference. The bill also has the support of antiabortion-rights religious leaders like Joel Hunter of Northland, Fla., and Derrick Harkins of Washington, D.C.The bill, which has been introduced in each of the past three congressional sessions, could "broker a detente" and help "turn down the volume on the culture war," DeLauro said at the press conference. Ryan called the bill an "idea whose time has come," noting that it has gained support from advocates on both sides of the abortion-rights debate.During the press conference, Hunter said advocates of the bill, regardless of their side in the abortion-rights debate, are "taking heat" from other members of their side. He added that the bill is important because it "links together traditional adversaries in a way that advances each of our goals without compromising any of our values" (Becker, "The Caucus," New York Times, 7/23). Harkins said that he is "more optimistic now than I ever have been," adding that women "need real support that divisive debates cannot provide" (Stephenson, CQ HealthBeat, 7/23).Despite support from some antiabortion-rights advocates, the bill has not been welcomed by all groups opposed to abortion rights, including conservative groups Family Research Council, National Right to Life and Democrats for Life of America. Kristen Day, executive director of Democrats for Life, said her group does not support the bill because preventing unintended pregnancies already is a goal of other programs. She noted that her group instead supports the Pregnant Women Support Act (HB 2035, SB 270), which focuses on services for women who carry their pregnancies to term but does not include prevention (CQ HealthBeat, 7/23). In a statement, Family Research Council President Tony Perkins said the bill is "fraught with funding for abortion providers and provisions that further encourage promiscuous sex and discourage parental involvement."Although the White House has not voiced a position on the bill, there are "reasons to believe" that the Obama administration will support some of the legislation"s proposals, "The Caucus" reports ("The Caucus," New York Times, 7/23). DeLauro said that she and Ryan plan to seek Republican co-sponsors for the bill, although they do not yet have any. She added that she thinks President Obama will support the bill because it includes language similar to his rhetoric on reducing the need for abortion. In addition, Obama"s chief of staff, Rahm Emanuel, was a co-sponsor of the bill when he served in the House (CQ HealthBeat, 7/23). Ryan said that the bill, which does not yet have an estimated cost, is "now open for support from all quarters."According to "The Caucus," the bill is being introduced at a time when abortion is a growing topic in health care reform legislation. Policymakers on both sides of the abortion-rights debate are expressing concern about how private insurance coverage of abortion is treated in health care reform. Ryan and DeLauro both support a policy that would neither require nor forbid insurance companies from covering the procedure ("The Caucus," New York Times, 7/23). During the press conference, DeLauro said that the new bill would not force insurance providers to cover abortion services. She said, "What we don"t want to do is go backward. We
"House Democrats spent another day Thursday negotiating their health reform overhaul with few concrete signs of progress, heightening tensions and raising the possibility that leaders might bypass the House Energy and Commerce Committee and send the bill straight to the floor," CongressDailyAM reports. "The seven Blue Dog Coalition members on the panel emerged from a three-hour meeting with leaders and White House officials Thursday afternoon with little to say" (Hunt and House, 7/24).
President Obama rallied support for health care at a town hall meeting in Shaker Heights, Ohio, on Thursday, despite news of a legislative delay in the Senate.
"President Barack Obama arrived at the Cleveland Clinic without fanfareò€¦ Thursday afternoon" to visit the medical center he"s called a model of low-cost, high-quality care, the Cleveland Plain Dealer reports. Obama said he wasn"t seeking an endorsement from the hospital, only information. "There has been a lot of discussion in Washington about the very different model that we and the Mayo [Clinic] have, and he wanted to understand it better," Clinic CEO Dr. Delos "Toby" Cosgrove said (Zeltner and Townsend, 7/24).
U.S. Secretary of Energy Steven Chu has announced that Energy Department-funded researchers have won 46 of the 100 awards given out this year by R&D Magazine for the most outstanding technology developments with promising commercial potential. The coveted awards are presented annually in recognition of exceptional new products, processes, materials or software developed throughout the world and introduced into the market the previous year.
Bell"s palsy is either weakness or paralysis of the muscles on one side of the face due to malfunction of the facial nerve. It usually starts suddenly - somebody can wake up in the morning and find that one side of the face does not move. Sometimes one eyelid may be affected, meaning that the patient is unable to blink properly from one eye.
The Minister for Health and Children, Mary Harney TD, welcomed the publication of the report of the independent audit of retained organs in the State by Michaela Willis.
The National Health and Hospitals Reform Commission has wasted a "once in a lifetime" opportunity to fix
CytRx Corporation (NASDAQ: CYTR), a biopharmaceutical research and development company engaged in the development of high-value human therapeutics, announced that its lead drug candidate tamibarotene has received official notification from the Committee for Orphan Medicinal Products (COMP) of the European Medicines Agency (EMEA) that a positive opinion was made regarding the application for orphan medicinal product for the treatment of acute promyelocytic leukemia (APL). The positive opinion of the COMP has now been forwarded to the EU commission for final approval and publication in the community register. This favorable opinion for tamibarotene in the European Union (EU) is in addition to the Orphan Drug Designation for APL and Fast Track Designation for the treatment of adult patients with relapsed or refractory APL following treatment with all-trans retinoic acid (ATRA) and arsenic trioxide granted by the U.S. Food and Drug Administration (FDA) in October 2007.
On Monday, the Health Ministries of Israel and Saudi Arabia reported their countries" first deaths from H1N1 swine influenza.
Medtronic, Inc. (NYSE: MDT) announced global resolution of all outstanding intellectual property litigation with Abbott Laboratories.
Quark Pharmaceuticals, Inc., a development-stage pharmaceutical company discovering and developing novel RNA interference (RNAi)-based therapeutics, announced data suggesting that QPI-1007 prevents progressive retinal ganglion cell (RGC) loss in an increased ocular pressure (IOP) rat model of glaucoma. The experiments performed by Prof. Adriana Di Polo of the Department of Pathology and Cell Biology, Universite de Montreal, indicate that QPI-1007 has the potential to treat patients with glaucoma. QPI-1007 is being evaluated in advanced IND-enabling preclinical studies as a neuroprotective agent for eye diseases.
A common food additive that gives M&Ms and Gatorade their blue tint may offer promise for preventing the additional and serious secondary damage that immediately follows a traumatic injury to the spinal cord. In an article published online in the Proceedings of the National Academy of Sciences, researchers report that the compound Brilliant Blue G (BBG) stops the cascade of molecular events that cause secondary damage to the spinal cord in the hours following a spinal cord injury, an injury known to expand the injured area in the spinal cord and permanently worsen the paralysis for patients.
Smoking has once again been implicated in the development of advanced cancer. Exposure to nicotine by way of cigarette smoking may increase the likelihood that pancreatic ductal adenocarcinoma will become metastatic, according to researchers from the Kimmel Cancer Center at Jefferson. Their study was published in the August edition of the journal Surgery.
The WHO on Friday said the "H1N1 swine-flu virus could infect up to two billion people over the next two years - about one of every three people in the world," VOA News reports. According to the news service, "A separate WHO report Friday said the virus has spread to almost every country in the world, killing about 800 people since it emerged in April" (7/25).
Congressional Republicans are releasing two health care reform proposals -- one from conservatives and one from moderates -- as alternatives to plans by Democrats, CQ Today reports (Wayne, CQ Today, 5/19). Conservative Plan
The House on Friday passed a $730.5 billion bill (HR 3293) "to fund health, education and labor programs in fiscal 2010 after narrowly defeating an attempt to strip language that would lift the ban on federal needle exchange programs," in the U.S., CQ Today reports (Wolfe, 7/24). Lawmakers voted 211-218 to reject an amendment by Mark Souder (R-Ind.) that sought to keep the ban in place, the AP/Lewiston Sun Journal reports (Taylor, 7/25). The bill that passed includes a restriction against using federal funds for needle exchanges within 1,000 feet of day care centers, schools, parks, playgrounds, pools and youth centers, the Washington Post reports.
A new study finds that most older long-term cancer survivors who are interested in diet and exercise actually have poor health habits. The study also reveals that those survivors who do exercise and watch their diet have improved physical health and quality of life. Published in the September 1, 2009 issue of Cancer, a peer-reviewed journal of the American Cancer Society, the research indicates that greater efforts are needed to encourage elderly cancer survivors to live healthier lives.
A comprehensive analysis of nearly 1,600 tumor samples has found that CT-X genes are expressed in nearly half the breast cancers that lack the estrogen receptor (ER). CT-X gene products are the targets of therapeutic cancer vaccines already in phase III clinical trials for lung cancer and melanoma. The study - to be published in the Early Edition of the Proceedings of the National Academy of Sciences this week - was led by the international Ludwig Institute for Cancer Research (LICR).
Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), July 28 - August 1, 2009, the foremost society for research into all aspects of eating and drinking behavior, finds that assisted reproductive techniques alter the expression of genes that are important for metabolism and the transport of nutrients in the placenta of mice. The results underscore the need for greater understanding of the long-term effects of new assisted reproductive techniques in humans.
The appropriate placement of automated external defibrillators (AEDs) is critical to optimize their use in public places, according to two studies published in Circulation: Journal of the American Heart Association.
A lack of sunlight is associated with reduced cognitive function among depressed people. Researchers writing in BioMed Central"s open access journal Environmental Health used weather data from NASA satellites to measure sunlight exposure across the United States and linked this information to the prevalence of cognitive impairment in depressed people.
A model of influenza transmission and treatment suggests that, if the current swine flu pandemic behaves like the 1918 flu, antiviral treatment should be reserved for the young. Researchers writing in the open access journal BMC Infectious Diseases found that, in this situation, providing the elderly with antiviral drugs would not significantly reduce mortality, and may lead to an increase in resistance.
Distinctive patterns of genes turned off - or left on - in healthy versus cancerous cells could enable early screening for many common cancers and maybe help avoid them, Medical College of Georgia scientists say.
Ovarian cancer kills approximately 15,000 women in the United States every
The University of Southern Nevada (USN) College of Nursing has been granted provisional approval by the Utah Board of Nursing to begin offering its 18-month Bachelor of Science in Nursing (BSN) program at the university"s campus located 10920 South River Front Parkway in South Jordan.
Capsule endoscopy for exploring the colon in a minimally invasive manner diagnoses 64% of all lesions located by means of conventional colonoscopy. According to a study published in The New England Journal of Medicine - the specialised medical journal with greatest international impact -, the new device would need technical improvements to achieve similar efficacy to the conventional procedure undertaken with a colonoscopy and to date considered a "gold standard" technique for this medical discipline, given that this is what currently provides the most reliable results. It has to be added that, moreover, conventional colonoscopy enables the undertaking of a diagnosis of the colon as well as practicing therapeutic procedures, such as the in situ extirpation of polyps during exploration or the obtaining of a biopsy when required.
Committees in the New Jersey Senate and Assembly on Monday unanimously approved a bill that would provide insurance benefits of up to $36,000 annually for autism treatments, the Philadelphia Inquirer reports. The funding, provided to developmentally disabled individuals younger than age 21, would go toward diagnostic services and early behavioral intervention, as well as occupational, physical and speech therapies. The Assembly could vote on the bill as early as Thursday, while the Senate bill is being considered by the state Senate Budget and Appropriations Committee.Sen. Loretta Weinberg (D), who sponsored the Senate bill, said, "I don"t know of any parent who wouldn"t do everything in their power to give their autistic or developmentally disabled child every chance to excel. However, the enormous cost of behavior intervention ... makes it out of the realm of possibility for many families." Assembly Speaker Joseph Roberts (D), who sponsored the Assembly bill, said, "In this economy, every New Jersey resident is struggling, but families with kids with special needs are struggling even more," adding, "They"re maxing out their credit cards and taking out second mortgages" to cover gaps in health insurance benefits.Citing cost issues, the New Jersey Business and Industry Association and the New Jersey Association of Health Plans were among those opposed to the bill. Christine Stearns, NJBIA vice president for health and legal affairs, said that the bill would make employer-sponsored insurance more costly and cause firms to drop such coverage, adding, "How, who and what is part of a basic health plan is all part of that." Stearns added that the bill is preferable to previous versions because it mandates that covered services be medically necessary and prescribed, places a reasonable cap on prices and ensures that the cost of educational services provided by schools is not shifted to insurers. Roberts said the bill would save money by delivering earlier treatment that could prevent more costly problems in the future (Henry, Philadelphia Inquirer, 5/19).
Celsion Corporation (NASDAQ: CLSN) and Yakult Honsha Co., Ltd. (Tokyo: 2267) announced that Celsion"s global Phase III ThermoDox trial for the treatment of primary liver cancer will be extended to Japan by Yakult"s expertise. This is an important step towards a potential application to market the drug in Japan. Yakult Honsha is the exclusive licensor of Celsion"s ThermoDox in Japan.
CSL Biotherapies, a subsidiary of one of the world"s leading manufacturers of thimerosal-free seasonal influenza vaccine, announced that it has begun shipment of its seasonal influenza virus vaccine to a national network of U.S. distributors for the 2009-2010 season. CSL Biotherapies plans to deliver more than eight million doses of the vaccine, the majority of which will be in single-dose, thimerosal-free, pre-filled syringes.
Since the groundbreaking 2002 ISAT International Subarachnoid Aneurysm Trial (ISAT) which ultimately was halted due to overwhelming evidence that minimally invasive coiling (an endovascular therapy) was, on average, superior to traditional surgical clipping in the treatment of brain aneurysms many studies have continued to prove the short and long-term viability of this procedure. Further technical refinements for coiling are underway all over the world.
Bioheart, Inc., (OTC Bulletin Board: BHRT) a company committed to delivering intelligent devices and biologics that help monitor, diagnose and treat heart failure and cardiovascular diseases announced today that the US FDA cleared a phase I clinical trial for MyoCell SDF-1 (Stromal Derived Factor - 1) to treat congestive heart failure. The REGEN trial will enroll 15 patients in a multicenter, randomized, dose escalation study to assess the safety and cardiovascular effects of the implantation of MyoCell SDF-1 in congestive heart failure patients post myocardial infarction(s).