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Lack Of Funds Prevents HIV-Positive People In Uganda From Receiving Antiretroviral Treatment
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Inhaled Growth Hormone Safe For Children Deficient In This Key Protein
A multi-center clinical trial led by a Riley Hospital for Children endocrinologist has found that inhaled growth hormone (GH) is well tolerated by children with GH deficiency and that this easy-to-use method can, over a one-week period, safely deliver GH to the blood stream. In addition to having implications for those who need GH, this first pediatric study of administering it through the lungs may also help researchers interested in using this convenient method for effectively delivering other types of medications to children.
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Aradigm Receives FDA Clearance For Phase IIb Clinical Trial Of Inhaled Liposomal Ciprofloxacin To Treat Bronchiectasis
Aradigm Corporation (OTCBB:ARDM) (the "Company") announced it received clearance from the U.S. Food and Drug Administration (FDA) for its inhaled liposomal ciprofloxacin Investigational New Drug (IND) application. The initial clinical protocol under this IND is an international, randomized, double-blind, placebo-controlled Phase IIb study designed to evaluate the Company"s inhaled liposomal ciprofloxacin in patients with non-cystic fibrosis bronchiectasis (BE). This orphan drug condition is a chronic severe respiratory disease and there is currently no drug specifically approved for its treatment in the U.S.
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Therapy Technique Cuts Divorce/Separation Rate By Nearly 50 Percent

Four simple questions on well-being asked at the start of each session of ongoing couples therapy can greatly increase chances for reconciliation and improved relationships, according to a newly published study. The largest clinical trial with couples to date, it shows that divorce and separation rates for couples that used this feedback technique were 46.2 percent less than that of couples who received therapy as usual. The findings, published in the August 3, 2009, Journal of Consulting and Clinical Psychology, are the results of a 2-year study conducted at the Vestfold Family Counseling Center in Norway by a U.S.-Norwegian team of researchers. From October 2005 to December 2007, 205 randomly selected couples receiving therapy in southern Norway participated in the study, which investigated the effects of providing ongoing feedback regarding the progress of treatment to both clients and therapists. The couples had problems typical of struggling relationships: communication difficulties, loss of feeling for partner, jealousy/infidelity, conflict, and coping with partner"s physical or psychological problems. Half of the study group had feedback incorporated into their therapy while the other half did not. Couples who used the feedback method rated their well-being on an individual, interpersonal, social, and overall basis by using a visual scale called the Outcome Rating Scale (ORS) at the beginning of each session. The results were used to guide each session: if progress was not noted, new directions for therapy were discussed and implemented. Therapists participating in the study received training on how to integrate the findings of the ORS and collaborate with couples to find new solutions. "Adding feedback can be the start of a revolution in couples therapy," said Dr. Barry Duncan, one of the authors of the study. "It encourages couples to honestly evaluate their progress and enables therapists to adjust therapy before it"s too late." Although feedback has been demonstrated to improve individual psychotherapy outcomes, no studies until now have examined couples therapy. Participants were contacted 6 months after the last therapy session. Respondents answered questions about their experience in treatment, including whether the couple remained together. The feedback couples were not only more satisfied with their relationships but also reported significantly lower rates of separation or divorce: a 18.4 percent separation/divorce rate for ORS couples versus 34.2 percent for non-ORS couples. This study adds to growing evidence that ongoing client feedback in psychotherapy can significantly improve outcomes. MyOutcomes, LLC


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