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ECRI Institute Calls For Allocating Comparative Effectiveness Funds For A National Patient Library
In testimony before the Listening Panel of the Federal Coordinating Council for Comparative Effectiveness Research (FCCC) on June 10, 2009, ECRI Institute President and Chief Executive Officer Jeffrey C. Lerner, Ph.D., called for devoting a substantial proportion of the $1.1 billion allocated to the comparative effectiveness research to go toward establishing a National Patient Library™. ECRI Institute® (http://www.ecri.org) is an independent nonprofit organization that researches the best approaches to improving patient care.
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Variations In 5 Genes Raise Risk For Most Common Brain Tumors
Common genetic variations spread across five genes raise a person"s risk of developing the most frequent type of brain tumor, an international research team reports online in Nature Genetics.
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Chicago Team Uses Artificial Intelligence To Diagnose Metastatic Cancer
When doctors are managing care for women with breast cancer, the information available to them profoundly influences the type of care they recommend. Knowing whether a woman"s cancer has metastasized, for instance, directly affects how her doctors will approach treatment -- which may in turn influence the outcome of that treatment.
Diagnostics

The Preclinical Natural History Of Serous Ovarian Cancer: Defining The Target For Early Detection

Ovarian cancer kills approximately 15,000 women in the United States every year, and more than 140,000 women worldwide. Most deaths from ovarian cancer are caused by tumors of the serous histological type, which are rarely diagnosed before the cancer has spread. In order to better understand the early natural history and to guide rational design of an early detection strategy for these cancers, Patrick Brown and colleagues from Stanford University developed models for the growth, progression, and detection of these cancers, in order to define what properties a biomarker-based screening test would require in order to be clinically useful. Funding: This work was funded by the Canary Foundation and the Howard Hughes Medical Institute. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors have declared that no competing interests exist. Citation: "The Preclinical Natural History of Serous Ovarian Cancer: Defining the Target for Early Detection." Brown PO, Palmer C (2009) PLoS Med 6(7): e1000114. doi:10.1371/journal.pmed.1000114 PLoS Medicine


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