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Minister Brady Launches The "Directory Of Services For Older People In The Stoneybatter" Area, Ireland
Aine Brady, T.D., Minister for Older People, officially launched the "Directory of Services for Older People in the Stoneybatter Area".
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Critical Marker Of Response To Gemcitabine In Pancreatic Cancer Identified By Jefferson Researchers
A protein related to aggressive cancers can actually improve the efficacy of gemcitabine at treating pancreatic cancer, according to a Priority Report in Cancer Research, published by researchers at Thomas Jefferson University.
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Daily Women's Health Policy Report Summarizes Studies Examining Ovarian Cancer
The following summarizes recent research related to ovarian cancer.~ Early periods linked to lower survival: Women who start menstruating at an early age or experience more menstrual cycles over their lifetimes appear to have a lower chance of surviving ovarian cancer, according to a study published this month in the journal Cancer Epidemiology, Biomarkers, and Prevention, Reuters reports. For the study, researcher Cheryl Robbins and colleagues analyzed the medical data of 410 ovarian cancer patients who participated in the Cancer and Steroid Hormone study between 1980 and 1982. The analysis found that the women who had their first period before age 12 had a 51% greater risk of dying than the women who began menstruating at age 14 or older. The women who had the highest number of lifetime menstrual cycles had a 67% greater risk of dying during follow-up than the women with the lowest number of cycles (Reuters, 7/24).~ Lung cancer risk higher for women after hysterectomy with ovary removal: Women who have had hysterectomies in which their uterus and both ovaries are removed to prevent ovarian cancer appear to have a higher risk for developing lung cancer, according to researchers at the University of Montreal, the New York Times reports. The researchers discovered the connection while looking for links between lung cancer and hormones for a study published in May in the International Journal of Cancer. Although they did not find a relationship between lung cancer risk and hormonal factors such as menstruation patterns, child-bearing or breastfeeding, the researchers found that women who had medically induced menopause had 1.92 times greater risk of developing lung cancer than women who had natural menopause (Caryn Rabin, New York Times, 7/24).~ Small tumors present for years before detection: Minute-sized ovarian tumors form and remain in the Fallopian tubes for an average of four years before they grow large enough to be detected, which might suggest why ovarian cancer frequently is diagnosed in its later stages, according to a study published in the journal PLoS Medicine, Reuters reports. For the study, lead researcher Patrick Brown of Stanford University and the Howard Hughes Medical Institute and colleagues analyzed the tumors of women whose Fallopian tubes and ovaries were removed because they had family histories of and genetic risk for ovarian cancer. They found small tumors -- most less than three millimeters in diameter -- that previously had not been detected in the women. In a statement, Brown said, "There is a long window of opportunity for potentially lifesaving early detection of this disease, but the tumor spreads while it is still much too small to be detected by any of the tests that have been developed or proposed to date." According to Reuters, blood tests for the compound called CA-125 may help guide therapy but do not indicate whether a woman has a tumor (Reuters, 7/28).
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Prostate Cancer Screening And Trust Of Physician Evaluated

Trusted health care s and continuity of care may help reduce the risk of prostate cancer deaths in African-American men, according to a study published in the current issue of the journal Cancer. James Mohler, MD, Chair of the Department of Urology at Roswell Park Cancer Institute (RPCI), and William R. Carpenter, PhD, Department of Health Policy and Management at the University of North Carolina, are lead investigators. The research analyzed physician trust, continuity of health care, the regular of health care and their effects on prostate cancer early detection among newly-diagnosed prostate cancer patients from North Carolina and Louisiana. The study enrolled 1,031 African-American and Caucasian-American men, age 50 and over, within weeks of their diagnosis of prostate cancer. A study nurse conducted a structured survey and acquired biological specimens in a home visit and abstracted medical information directly from medical records. In this study, the stage of prostate cancer at diagnosis was similar between races, but the mean Gleason scores, an indication of the aggressiveness of the disease, were higher for African-Americans than Caucasian-Americans. African-Americans were less likely than Caucasians to report participation in prostate cancer screening prior to diagnosis. Men without a prior history of screening were more likely to be diagnosed with advanced disease and/or more aggressive forms of prostate cancer. However, when men of either race had established relationships with the same health care provider, these differences in prostate cancer aggressiveness went away. Therefore, addressing racial differences in use of screening may reduce racial disparities in prostate cancer diagnosis and treatment, and, by extension, may reduce disparities in prostate cancer deaths. "The goal of the study was to gain a deeper understanding of the role of racial disparities in prostate cancer outcomes," said Dr. Mohler. "These findings suggest that differences in screening result from inconsistent or poorer quality interaction between an African-American man and the American health care system. If the interaction is poor, the care giver may not get around to discussing or offering preventive health care, such as prostate cancer screening. Improving the interaction between all men, and especially African-American men, and their primary care givers should reduce prostate cancer deaths in all men and decrease the racial disparity in prostate deaths in African-American men." Dr. Carpenter added, "Factors in health care systems, including setting and continuity of care, may hinder the development of physician-patient relationships. These factors may preclude or limit discussions about preventive health care and early detection of disease through prostate cancer screening." The mission of Roswell Park Cancer Institute (RPCI) is to understand, prevent and cure cancer. RPCI, founded in 1898, was one of the first cancer centers in the country to be named a National Cancer Institute-designated comprehensive cancer center and remains the only facility with this designation in Upstate New York. The Institute is a member of the prestigious National Comprehensive Cancer Network, an alliance of the nation"s leading cancer centers; maintains affiliate sites; and is a partner in national and international collaborative programs. Roswell Park Cancer Institute


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