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Celsion And Yakult Honsha Announce Start-up Of Japanese Clinical Trial Sites In Celsion's Global Phase III ThermoDox(R) Trial For Primary Liver Cancer
Celsion Corporation (NASDAQ: CLSN) and Yakult Honsha Co., Ltd. (Tokyo: 2267) announced that Celsion"s global Phase III ThermoDox trial for the treatment of primary liver cancer will be extended to Japan by Yakult"s expertise. This is an important step towards a potential application to market the drug in Japan. Yakult Honsha is the exclusive licensor of Celsion"s ThermoDox in Japan.
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Paclitaxel Poliglumex (OPAXIO(TM)) Added To Cisplatin And Radiation Produces 45% Pathologic Complete Remissions In Patients With Esophageal Cancer
Cell Therapeutics, Inc. ("CTI") (Nasdaq and MTA: CTIC) announced that, in a study released from Brown University at the 2009 American Society for Clinical Oncology (ASCO) Annual Meeting, patients with cancer of the lower esophagus had evidence of a high pathological complete response ("CR") rate when given OPAXIO, a biologically enhanced paclitaxel, in addition to cisplatin and full-course radiotherapy.
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Sexually Transmitted HPV Linked To Certain Head & Neck Cancers
Researchers at Roswell Park Cancer Institute (RPCI) in Buffalo, New York, are strongly advocating a national discussion about the need to vaccinate both young men and women against HPV 16 to prevent head & neck cancers. The call comes amid growing evidence that certain cancers of the head and neck are strongly linked to HPV 16, a specific strain of the human papillomavirus (HPV) that is one of the most common sexually transmitted diseases in the United States. It is estimated that approximately 70% of Americans, both men and women, will be infected with HPV at some point in their lives.
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Nightmares Predict Elevated Suicidal Symptoms

Self-reported nightmares among patients seeking emergency psychiatric evaluation uniquely predicted elevated suicidal symptoms, according to a research abstract presented at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies. Results indicate that severe nightmares were independently associated with elevated suicidal symptoms after accounting for the influence of depression, whereas symptoms of insomnia were not. These findings suggest that nightmares stand alone as a suicide risk factor. The sample included 82 men and women between the ages of 18 and 66, who were in a community mental health hospital admissions unit awaiting an emergency psychiatric evaluation. Evaluations determined eligibility for crisis stabilization inpatient admittance. Patients" nightmares, insomnia, depression and suicidal tendencies were assessed through several questionnaires, including the Disturbing Dreams and Nightmare Severity Index, Insomnia Severity Index (ISI), Beck Depression Inventory (BDI), and the Beck Scale for Suicide Ideation (BSS). According to principal investigator, Rebecca Bernert, doctoral candidate in clinical psychology at Florida State University, findings of the study emphasize the need for a more thorough assessment of sleep among acutely-ill patients, as it may be an important opportunity for intervention. "Sleep disturbances, especially nightmares, appear to be an acute warning sign and risk factor for suicide," said Bernert. "Given that poor sleep is amenable to treatment, and less stigmatized than depression and suicide, our findings could impact standardized suicide risk assessment and prevention efforts." The study states that sleep complaints are now listed among the top 10 warning signs of suicide by the Substance Abuse and Mental Health Services Administration (SAMHSA). Sleep and mood disturbances are closely related, and depression is the single best predictor of suicide. People who suffer from persistent sleep problems should consult a sleep expert at one of the 1,600 centers accredited by the American Academy of Sleep Medicine (AASM). Those experiencing a suicidal crisis or emotional distress are encouraged to contact the National Suicide Prevention Lifeline, which offers a 24-hour crisis hotline. Abstract Title: Insomnia and Nightmares as Predictors of Elevated Suicide Risk Among Patients Seeking Admission to Emergency Mental Health Facility Presentation Date: Tuesday, June 9 Category: Sleep in Psychiatric Disorders Abstract ID: 1120 Kelly Wagner American Academy of Sleep Medicine


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