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Potentially Dangerous Drug Interactions Missed By Prescribers
Research led by The University of Arizona College of Pharmacy has found that medication prescribers correctly identified fewer than half of drug pairs with potentially dangerous drug-drug interactions.
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In Mouse Study Immune Cells Ameliorate Hypertension-Induced Cardiac Damage
Researchers in Berlin, Germany have found that a specific type of immune cell, the regulatory T lymphocyte (Treg) plays an important role in hypertension-induced cardiac damage. The injected Treg that they harvested from donor mice into recipient mice were infused with angiotensin II, a blood pressure-raising peptide. The Tregs had no influence on the blood pressure response to angiotensin II. Nonetheless, cardiac enlargement, fibrosis, and inflammation was sharply reduced by Treg treatment. Furthermore, the tendency to develop abnormal heart rhythms that could lead to sudden cardiac death was also reduced. Dr. Heda Kvakan and Dr. Dominik N. MÃøller at the Experimental and Clinical Research Center at the Max DelbrÃøck Center do not intend Treg as a therapy. However, a better understanding of how the immune system fits into hypertension-induced organ damage could result from these studies (Circulation, Vol. 119, No. 22, June 9, 2009, 2904-2912 ).*
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H1N1 Confirmed In Three More African Countries; Cambodia, Indonesia Confirm First Cases

The H1N1 (swine flu) virus has reached the sub-Saharan African countries of Cape Verde, Ethiopia and Ivory Coast, according to the WHO, the AP/Boston Herald reports. Last week, South Africa became the first country in the region to confirm a 12-year-old, who had returned from the U.S., tested positive for the H1N1 virus. "WHO says African countries are particularly vulnerable because of their fragile health care systems and the widespread presence of other health problems such as HIV and tuberculosis," the AP/Boston Herald writes (AP/Boston Herald, 6/24). There have been no newly confirmed cases of H1N1 in Ethiopia since two patients tested positive for the virus last week, according to the Ethiopian Minister of Health, Ethiopian Review reports (Tesfaye, Ethiopian Review, 6/24). The WHO and Cambodian health officials on Wednesday confirmed that a 16-year-old American girl visiting Cambodia has become the country"s first confirmed case of H1N1, Reuters reports. Also on Wednesday, health officials in Indonesia confirmed the country"s first cases of H1N1 in Jakarta and the island of Bali. "Health Minister Siti Fadillah Supari ò€¦ said she was concerned that if H1N1 got a foothold in Indonesia there was a risk it could combine with the much deadlier H5N1 bird flu virus," Reuters writes (Madra, Reuters, 6/24). This information was reprinted from globalhealth.kff.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Global Health Policy Report, search the archives and sign up for email delivery at globalhealth.kff.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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