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Revealing Leukemia-Initiating Cells
Two new studies reveal a way to increase the body"s appetite for gobbling up the cancer stem cells responsible for acute myeloid leukemia (AML), a form of cancer with a particularly poor survival rate. The key is targeting a protein on the surface of those cells that sends a "don"t eat me" signal to the macrophage immune cells that serve as a first line of defense, according to the reports in the July 24th issue of the journal Cell, a Cell Press publication.
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Gastrin Plays Significant Role In Helicobacter-Induced Stomach Cancer
A group led by Columbia University Medical Center"s Timothy Wang, M.D., has studied the role of Helicobacter infection in the development of stomach cancer and found that the hormone gastrin, which stimulates secretion of gastric acid, plays a key role in the development of Helicobacter-induced stomach cancer, and may have distinct effects on carcinogenesis in different parts of the stomach.
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Baltimore Sun Examines Debate Over Howard County, Md., Health Program

About 200 uninsured people have enrolled in the Howard County, Md., Healthy Howard program since it began on Oct. 1, 2008, county health officer Peter Beilenson told a county council budget panel, the Baltimore Sun reports. Healthy Howard is a network of local doctors who charge members between $50 and $115 monthly for comprehensive medical coverage. The program uses health coaches to improve residents" overall health and seeks to lower costs related to emergency care over time. Beilenson had set a goal of enrolling 2,000 people in the program"s first year. According to Beilenson, "The biggest problem with all this is me. I made the definition of success this arbitrary 2,000 number." His new prediction is for 908 enrollees by July 2010. He said, "I think it"s very clear people just don"t know about it." He added that some residents are hesitant to pay even a small monthly charge during the continuing recession. County council member Greg Fox questioned if the enrollment level justifies a second county outlay of $500,000 for the program in fiscal year 2010, adding that he supports cutting county funding in half for the program in that year. Supporters of the program, however, say it needs more time and money in order to succeed, noting that enrollees have been seeing doctors through the program only since January. Commonwealth Fund President Karen Davis said the program "seems like it"s off to a great start" compared with similar local programs nationwide. She added that the program has helped 2,500 county residents, including children, find coverage through state and federal insurance programs, in part thanks to an electronic enrollment system that identifies programs they are eligible for. Howard Health Department Director of Policy and Planning Glenn Schneider said, "None of those applications would have happened without announcing the (Healthy Howard) program" (Carson, Baltimore Sun, 5/18). Reprinted with kind permission from http://www.kaisernetwork.org. You can view the entire Kaiser Daily Health Policy Report, search the archives, or sign up for email delivery at http://www.kaisernetwork.org/dailyreports/healthpolicy. The Kaiser Daily Health Policy Report is published for kaisernetwork.org, a free service of The Henry J. Kaiser Family Foundation. © 2009 Advisory Board Company and Kaiser Family Foundation. All rights reserved.


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