Categories
Cardiovascular
Diagnostics
Endocrinology
Health Insurance
Medical Devices
Mental Health
Nutrition
Oncology
Public Health
Sexual Health
shop dildos - is great for every girl.
Popular Articles

Australian Medical Association To Work With Government On Nurse Legislation
The Australian Medical Association will work with the Federal Government to ensure patients benefit from the introduction of new prescribing rights for nurse practitioners and midwives.
drugs without prescription
What Is Lyrica (pregabalin)? What Does Lyrica Treat?
Lyrica is Pfizer"s trade name for a drug called pregabalin. Pregabalin is an anticonvulsant (anti-seizure) drug that is often used to treat neuropathic pain as well as partial seizures that are common in temporal lobe epilepsy. In Europe, pregabalin is also approved to treat generalized anxiety disorder.
News of the day
Serum Bile Acid Profiling For Inflammatory Bowel Disease Characterization
Based on serum bank material, BA profiling was applied in IBD patients and healthy controls which showed that most but not all BA species were decreased to a different extent in CD and UC. BA decreases were highly pronounced in CD patients with surgical interventions in the gut. On the other hand, UC patients with additional liver and gallbladder diseases showed clearly increased levels of those BAs that are synthesized directly in the liver (primary BAs), or subsequently modified by intestinal bacteria (secondary BAs). Furthermore, a marked decrease in the toxic BA lithocholic acid (LCA) was found together with a marked increase in its physiological detoxification product, hyodeoxycholic acid (HDCA), irrespective of the IBD phenotype or clinical manifestation, which showed accelerated detoxification activity in IBD patients. Thus, serum BA profiling might serve as an additional diagnostic tool for IBD characterization and differentiation. In combination with expression profiles of nuclear pregnane X receptor (PXR)-regulated genes, it might allow us to estimate the BA detoxification potential of IBD patients.
Oncology

A Potential Treatment For Gastric Motility Disorders

GES or pacing has been under investigation as a potential therapy for gastrointestinal motility disorders. Conventionally, GES is performed using a single pair of electrodes or single-channel GES. However, few studies have investigated the effects of two-channel GES with trains of pulses on gastric motility, such as gastric slow waves and gastric emptying. The research team led by Prof. Chen from University of Texas Medical Branch studied the effects of two-channel GES with trains of pulses on gastric slow waves and gastric emptying in healthy dogs. Most previous studies showed that long pulse GES was able to entrain gastric slow waves in human and animals. None of previous studies have investigated the effect of GES with trains of pulses on gastric slow waves. It has been indicated that GES with trains of short pulses was able to improve symptoms, such as nausea and vomiting of gastroparesis, but was not capable of entraining gastric slow waves or normalizing gastric dysrhythmias. In this study, we have shown that GES with trains of pulses is able to entrain gastric slow waves when the pulses in the train are of a width of 4ms or higher. Recently, a few studies were performed to investigate the efficiency of multi-channel GES on gastric emptying and entrainment of slow waves. Some studies indicated that multi-channel stimulation with long pulses was more efficient than single-channel stimulation for the entrainment of slow waves and the acceleration of gastric emptying. To date, no study has investigated the effects of multi-channel GES with trains of pulses on gastric emptying. In our experiment, we found two-channel but not single-channel GES with trains of pulses significantly accelerated gastric emptying. The results of our study suggest that 2-channel GES with trains of pulses may be applicable for the treatment of gastroparesis and normalization of gastric dysrhythmia. GES with trains of pulses is technically more attractive than long pulse GES. Currently, most of commercially available implantable stimulators use trains of pulses. However, none of available implantable stimulators are capable of generating pulses with a width equal to or larger than 4ms. Therefore, new hardware design and development are needed. Reference: Yang B, Hou XH, Song GQ, Liu JS, Chen JDZ. Effect of two-channel gastric electrical stimulation with trains of pulses on gastric motility. World J Gastroenterol 2009; 15(19): 2406-2411 Correspondence to: Dr. Jiande DZ Chen, Department of Gastroenterology, University of Texas Medical Branch, 301 University Blvd, Basic Science Building, Room 433, Galveston, TX 77555-0655, United States. Jian-Xia Cheng World Journal of Gastroenterology


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):

© Copyright 2009